Wednesday, 01 February 2012 12:00
Microsoft may try to revive support for Hyper-V in OpenStack as the community considers removing the code -- which one OpenStack developer called broken and unmaintained -- from the stack.
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Wednesday, 01 February 2012 12:00
Facebook is expected to apply within hours to sell stock on the open market in what will be the most talked-about initial public offering since Google in 2004, maybe since the go-go 1990s.
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Wednesday, 01 February 2012 12:00
 This tutorial covers the issues concerning the creation and pre-press workflow of a vector file. When creating an artwork that you are going to print, you should take into consideration the design’s technical factors. Phantasm CS allows you to quickly analyse and prepare the created artwork for printing. Let’s get started!  Advertise here via BSA 
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Wednesday, 01 February 2012 12:00
 DealFuel is here. The best thing to happen since bearded dragons learnt how to play ant crusher :) And we’re kicking things off with 4 cool tech deals for: Web devs who want to profit from their talent jQuery wanna-bees and students Designers who are keen to work faster Website owners who demand peace-of-mind There’s something for everyone! We [...]
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Tuesday, 31 January 2012 12:02
Ever wondered what condiments are benefiting you and what condiments are hurting you? Here is a great article that will tell you exactly what condiments you should stay away from and what is okay to add to your daily lifestyle. Enjoy! The top 5 healthiest condiments (and the WORST)
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Tuesday, 31 January 2012 12:02
Have you ever noticed while working on the PC that the longer you work the slower the system seems to be. This is all because of the so many process running in the background which consumes a lot of memory. Though some of them may be really required by the windows process but still there [...]
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Tuesday, 31 January 2012 12:01
January 30, 2012 (MMD Newswire) -- Today, Erivedge (vismodegib) was approved by the U.S. Food and Drug Administration to treat adult patients with basal cell carcinoma, the most common type of skin cancer. The drug is intended for use in patients with locally advanced basal cell cancer who are not candidates for surgery or radiation and for patients whose cancer has spread to other parts of the body (metastatic).
Erivedge, reviewed under the agency's priority review program, is the first FDA-approved drug for metastatic basal cell carcinoma. Erivedge was reviewed under the FDA's priority review program that provides for an expedited six-month review of drugs that may offer major advances in treatment. The drug is being approved ahead of the March 8, 2012 prescription user fee goal date.
Basal cell carcinoma is generally a slow growing and painless form of skin cancer that starts in the top layer of the skin (epidermis). The cancer develops on areas of skin that are regularly exposed to sunlight or other ultraviolet radiation.
Erivedge is a pill taken once a day and works by inhibiting the Hedgehog pathway, a pathway that is active in most basal cell cancers and only a few normal tissues, such as hair follicles.
"Our understanding of molecular pathways involved in cancer, such as the Hedgehog pathway, has enabled the development of targeted drugs for specific diseases," said Richard Pazdur, M.D., director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research. "This approach is becoming more common and will potentially allow cancer drugs to be developed more quickly. This is important for patients who will have access to more effective therapies with potentially fewer side effects."
The safety and effectiveness of Erivedge was evaluated in a single, multi-center clinical study in 96 patients with locally advanced or metastatic basal cell carcinoma. The clinical study's primary endpoint was objective response rate (ORR) or the percentage of patients who experienced complete and partial shrinkage or disappearance of the cancerous lesions after treatment. Of the patients with metastatic disease receiving Erivedge, 30 percent experienced a partial response and 43 percent of patients with locally advanced disease experienced a complete or partial response.
The most common side effects observed in patients treated with Erivedge were muscle spasms, hair loss, weight loss, nausea, diarrhea, fatigue, distorted sense of taste, decreased appetite, constipation, vomiting, and loss of taste function in the tongue.
Erivedge is being approved with a BOXED WARNING alerting patients and health care professionals of the potential risk of death or severe birth effects to a fetus (unborn baby). Pregnancy status must be verified prior to the start of Erivedge treatment. Male and female patients should be warned about these risks and the need for birth control.
Erivedge is marketed by South San Francisco based-Genentech, a member of the Roche Group.
For more information:
FDA: Office of Hematology and Oncology Products
FDA: Approved Drugs: Questions and Answers
The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation's food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.
Source: FDA
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Tuesday, 31 January 2012 12:01
Overnight Domestic Shipping Up to 70 Pounds for $39.95
Release No. 12-018
WASHINGTON (MMD Newswire) January 27, 2012 -- Expanding on the success of its line of Priority Mail Flat Rate Boxes, the U.S. Postal Service has introduced the first Express Mail Flat Rate Box.
Ideal for consumers and small businesses selling merchandise online, the Postal Service's Express Mail Flat Rate Box takes the guess work out of shipping, providing overnight delivery -- up to 70 pounds -- almost anywhere in the country for $39.95.
"With the Express Mail Flat Rate Box, there's no need to use a zone chart to calculate prices. If it fits, it ships," said Gary Reblin, vice president, Domestic Products. "The Express Mail Flat Rate Box offers convenience, ease of use, free packaging and a flat-out value price."
Express Mail Flat Rate Boxes also can be used for international shipments with a maximum weight of 20 pounds. The boxes are priced at $59.95 to Canada and $74.95 for all other countries that accept Express Mail International.
The Express Mail Flat Rate Box rounds out the Express Mail Flat Rate product line, which includes an Express Mail Flat Rate Envelope and an Express Mail Flat Rate Legal Envelope, both retailing for $18.95.
The same size as the medium Priority Mail Flat Rate Box, the Express Mail Flat Rate Box is available in a top-loading or side-loading design. The boxes can be ordered online at usps.com and also are available at select Post Offices.
Express Mail service offers a money-back guarantee (some restrictions apply) and overnight delivery to most U.S. addresses, including PO Boxes. Express Mail is delivered 365 days a year with no Saturday delivery charges, residential surcharges or fuel surcharges. Sunday and holiday delivery is available to many ZIP codes for a modest premium.
Free Package Pickup and delivery status information using the Track & Confirm tool are available at no cost when shipping online at usps.com.
The Postal Service receives no tax dollars for operating expenses and relies on the sale of postage, products and services to fund its operations.
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Tuesday, 31 January 2012 12:01
Florida Company to Produce Environmentally Friendly, Cheap & Efficient Alternative Lighting
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TAMPA, FL., (MMD Newswire) January 30, 2012 -- TBSS International, Inc. ("TBSS"), announced in December, 2011, that they had purchased the patents, inventory and molds of a highly efficient and environmentally-friendly neon lighting system (Velella Lighting Systems: VLS) that was created initially for the nesting of sea turtles.
TBSS is commencing a pilot program along Florida beaches to assess the effectiveness of its recently acquired energy-efficient neon lighting manufactured under the specifications required by the Turtle Conservation Coastal Lighting Regulations.
Sea turtles in Florida and other coastal states nest almost always under the cover of night to protect themselves from predators and overheating. As a result of this survival instinct, beach resorts and beach homes are prohibited from using flood lights, which impede nesting and limit beach activity at night due to safety concerns. The company believes that the market for "turtle compliant" lighting on beachfront properties, including marinas, hotels and residences is huge.
The publicly held company announced on January 24th that their engineers had completed the design phase of new commercial lighting applications for office workspace and outside path lighting, and mass production of the newly designed 2' x 4' lay-in fixtures will begin in the coming weeks. The company's design maximizes the visible light while minimizing wattage usage. The Velella Lighting System, which is designed to run on a patented 12 volt DC power supply, meets or exceeds requirements set by Underwriters Laboratory (UL) and Independent Electrical Engineering Reports, and will be brighter, safer, and cheaper to operate.
Todd Spinelli, CEO of TBSS, noted, "As Congress forces all of us to gradually discontinue use of incandescent lighting in deference to the new compact fluorescent lights (CFL), we will all pay more up front, and worry about the dangers and strict regulations that surround disposal of the expensive CFL's. The VLS alternative is already in use through a number of trial programs in street lights in half a dozen neighborhoods across the country. Utility statements indicate that the VLS is 85% more efficient than incandescent lighting and at least 50% more efficient than last generation fluorescent lighting. When compared to the environmental headaches that surround the new CFL screw-in bulbs, the VLS neon light will be 60% cheaper in initial cost, will not contain deadly mercury, and require no special procedures for disposal. We anticipate having a consumer (screw in) version of the VLS by late summer 2012."
Velella Lighting System Benefits Summary vs. LED Lighting
- Velella Lights are non-corrosive unlike LED lights
- Velella Lights have up to a 28 year lifespan vs. up to 4 year Limited warranties for identified competitive LED products*
- Velella Lights have higher longevity, lower replacement rates and therefore lower maintenance costs than LED
- Velella Lights are competitive or lower in price than LED light alternatives*
- LED lights have serious disposal/land fill issues due to quantities of nickel and lead heavy metals and other toxic components
- Velella Lights use less energy than LED lights in a DC (Direct Current) form*
- Velella Lights give off no heat and LED lights radiate heat. Therefore, Velella Lights do not measurably impact cooling cost and by definition are more efficient in use of electricity
- Neon Velella Lights are physiologically more comfortable to the human eye reducing eye strain and possible damage caused by harsher LED light illumination, as per American Eye Association studies
*further specific details are subject to specific analysis of various LED lighting products on the market.
ANNUAL OFFICE LIGHTING OPERATING COST COMPARISON
30 Standard Industrial 2'x 4' - 4 Bulb Fluorescent fixtures
- Annual Electricity Cost - ($162.01 per unit x 30) = $4,860.30
- Annual Cooling Cost - $601.92
- Annual Maintenance Costs - $31.14 per unit x 30 = $934.20
- Total Fluorescent Lighting Office Costs = $6,396.42
30 Vellela 2' x 4' - 5 Bulb Commercial Fixture
- Annual Electricity Cost - ($15.75 per unit x 30) = $472.50
- Annual Cooling Cost = $0
- Annual Maintenance Costs = $0
- Total Vellela Light Office Costs = $472.50
- Average Annual Savings using Vellela Lightning International = $5,923.92
Spinelli adds, "We are proud to be able to bring this safe and energy-efficient lighting product to the public. The product has proven itself in parking lots, beach lighting and residential street lighting, and is a viable alternative to traditional incandescent and fluorescent lights including the expensive CFL that Congress is jamming down our throats. TBSS will be manufacturing VLS products in the Pensacola, FL area and has plans to open additional facilities across the country. Initially the company expects to employ close to 1,000 people, a significant boost to Florida's unemployment. As production gears up and manufacturing is moved to the U.S., and facilities are opened across the country, TBSS will need to fill thousands of positions in manufacturing, and marketing. In addition to saving Americans dollars up front and operational costs for lighting, we hope to impact the job market in a big way."
About TBSS International, Inc.
TBSS International is a domestic and international service company with service contracts in different sectors such as gold mining, oil drilling, water well drilling, trenching and construction and recently entered the energy efficient lighting market. The management team of TBSS has been in the construction industry since 1950 with a strong reputation for completing contracts on time and within budgets. TBSS's competitive advantage stems from the company's joint venture partners, their respective technological expertise and proprietary technology and the company's own intellectual property. The corporate website is at http://www.tbssinternational.com
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Tuesday, 31 January 2012 12:01
TEANECK, NJ (MMD Newswire) January 27, 2012 -- Chandrasekaran Ramakrishnan sold 5,000 shares of Cognizant Technology Solutions Corp stock, or $355,300 worth, as noted in an SEC Filing today. As reported in the filing, the transactions occurred on January 24, 2012.
After the transaction, Chandrasekaran Ramakrishnan's stake was reported as 78,083 shares of Cognizant Technology Solutions Corp stock (a 6% decrease from before the transaction took place). In addition, Chandrasekaran Ramakrishnan performed several other transactions, including using transaction codes 'M' (exercise, usually of options). Chandrasekaran Ramakrishnan's title was listed as "Pres. & MD, Global Delivery" at Cognizant Technology Solutions Corp within the filing.
As noted on January 26, 2012, Chandrasekaran Ramakrishnan's sale was done directly over 1 transaction on January 24, 2012. The share price for the transaction was $71.06 according to the regulatory filing detailing the trade.
If we look over the past 12 months, Chandrasekaran Ramakrishnan has sold a total of 76,000 shares of Cognizant Technology Solutions Corp, proceeds from the sale totaled $5,319,850. Over the same time period, Chandrasekaran Ramakrishnan has purchased no shares of Cognizant Technology Solutions Corp stock. Chandrasekaran Ramakrishnan has also performed other transactions including grants or awards , payment of tax liabilites , and exercise of options .
Let's take a quick, high-level look at insider trading at Cognizant Technology Solutions Corp over the past 12 months. A total of 248,593 shares of Cognizant Technology Solutions Corp stock was sold by insiders, totaling $18,654,610. Over the same time 12 month time period, no shares of Cognizant Technology Solutions Corp were purchased by company insiders.
Source: SEC Filings
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Tuesday, 31 January 2012 12:01
LITTLETON, CO (MMD Newswire) January 27, 2012 -- Derek Johnson sold 2,600 shares of Ada-es Inc stock, or $55,610 worth, as noted in an SEC Filing today. As reported in the filing, the transactions occurred between January 24, 2012 - January 25, 2012.
After the transaction, Derek Johnson's stake was reported as 23,693 shares of Ada-es Inc stock (a 9% decrease from before the transaction took place). Derek Johnson's title was listed as "Director" at Ada-es Inc within the filing.
As noted on January 26, 2012, Derek Johnson's sale was done directly over 3 transactions from January 24, 2012 to January 25, 2012. The share price ranged from $21.17 to $22.05 according to the regulatory filing detailing the transactions.
If we look over the past 12 months, Derek Johnson has sold a total of 6,100 shares of Ada-es Inc, proceeds from the sale totaled $135,789. Over the same time period, Derek Johnson has purchased no shares of Ada-es Inc stock. Derek Johnson has also performed other transactions including grants or awards .
Let's take a quick, high-level look at insider trading at Ada-es Inc over the past 12 months. A total of 49,040 shares of Ada-es Inc stock was sold by insiders, totaling $1,114,657. Over the same time 12 month time period, no shares of Ada-es Inc were purchased by company insiders.
Source: SEC Filings
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Tuesday, 31 January 2012 12:01
NASHVILLE, TN (MMD Newswire) January 27, 2012 -- Bank Of America Corp /de/ sold 171,623 shares of Hca Holdings, Inc stock, or $4,381,947 worth, as noted in an SEC Filing today. As reported in the filing, the transactions occurred on January 24, 2012.
After the transaction, Bank Of America Corp /de/'s stake was reported as 3,358,710 shares of Hca Holdings, Inc stock (a 4% decrease from before the transaction took place).
As noted on January 26, 2012, Bank Of America Corp /de/'s sale was done indirectly through "By Subsidiary" over 1 transaction on January 24, 2012. The share price for the transaction was $25.53 according to the regulatory filing detailing the trade.
If we look over the past 12 months, Bank Of America Corp /de/ has sold a total of 21,172,054 shares of Hca Holdings, Inc, proceeds from the sale totaled $611,544,485. Over the same time period, Bank Of America Corp /de/ has purchased 5,044 shares of Hca Holdings, Inc, with a total cost of $151,703. Bank Of America Corp /de/ has also performed other transactions including dispositions .
Let's take a quick, high-level look at insider trading at Hca Holdings, Inc over the past 12 months. A total of 188,407,240 shares of Hca Holdings, Inc stock was sold by insiders, totaling $5,497,564,363. Over the same time 12 month time period, 749,799 shares of Hca Holdings, Inc, for a total value of $72,748,382 were purchased by company insiders.
Source: SEC Filings
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